RAF Typhoon FGR4s have joined forces with France's air force in a joint strike against an hidden munitions depot in Syrian territory used by the Daesh militant organization, per a report from the UK's MoD.
The location, identified by reconnaissance, was believed to be storing arms and explosives, the statement said, and was located in mountainous terrain just north of the historic site of Palmyra in Syria's central region.
"The RAF jets used Paveway IV guided bombs to strike a number of approach shafts providing entry to the site... early reports suggest the strike was effective," officials stated.
There was no indication of any harm to civilians in the attack on Saturday evening and all the aircraft returned to base without incident, the defence officials confirmed.
The British jets were supported by a Voyager aerial refuelling aircraft.
The Islamic State group - also known as the so-called Islamic State - imposed extremist governance over large swathes of both Syria and Iraq until 2019.
"This strike underscores our UK leadership, and determination to operate in unison with allied nations, to eradicate any resurgence of Daesh and their dangerous and violent ideologies in the area," the British Defence Secretary John Healey stated.
RAF aircraft have performed overwatch operations over Syrian airspace to "forestall any attempted comeback" of Islamic State after its defeat at the Baghuz confrontation in 2019, the authorities noted.
"I want to thank every member of British forces who took part in this operation for their expertise and their bravery," Healey added. "They were part of thousands of British troops stationed over the festive period. This action, to remove terrorist threats who endanger our way of life, demonstrates how British military are ready to step up, throughout the year, ensuring Britain's security domestically and strong abroad."
Last December, the US military conducted what it described as a "major assault" against IS targets in Syria, subsequent to an ambush killed two US servicemembers and a civilian linguist in the Palmyra area.
The UN says Daesh still boasts roughly 5-7 thousand combatants in Syria and Iraq.